| 发明名称 |
ASYMMETRIC SYNTHESIS OF Ó-CYCLOALKYLALKYL SUBSTITUTED METHANAMINES |
| 摘要 |
This invention relates to processes for asymmetrically producing enantiomerically pure .alpha.cycloalkylalkyl substitututed methanamines from .alpha.-pinene. One key step of the process of this invention utilizes the oxidation product of .alpha.-pinene, hydroxy pinanone, as a chiral auxiliary to direct the stereoselective alkylation of the corresponding ketimine. This invention also relates to key intermediates useful in the processes referred to herein.
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| 申请公布号 |
CA2192417(A1) |
申请公布日期 |
1997.06.12 |
| 申请号 |
CA19962192417 |
申请日期 |
1996.12.09 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
ROTH, GREGORY P.;LANDI, JOHN J., JR. |
| 分类号 |
C07D213/36;B01J31/02;C07B53/00;C07B61/00;C07C29/48;C07C45/28;C07C45/29;C07C49/513;C07D213/53;(IPC1-7):C07D213/53;C07D271/06;C07C271/12;C07C251/20;C07D333/22;C07C35/28;C07C317/28;C07D277/28;C07C49/433;C07C323/45;C07D233/64 |
主分类号 |
C07D213/36 |
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