发明名称 |
PROCESS FOR PREPARING 2-CHLOROTHIAZOLE COMPOUNDS |
摘要 |
The invention relates to a process for preparing a compound of formula (I), in which X is CH or N, Y is NO2 or CN, Z is CHR3, O, NR3 or S, R1 and R2 are either each, independently of the other, hydrogen or unsubstituted or R4-substituted alkyl or together a two- or three-membered alkylene bridge or a two- or three-membered alkylene bridge in which one member is replaced by a hetero member selected from the group, consisting of NR5, O and S, R3 is H or unsubstituted or R4-substituted alkyl, R4 is an unsubstituted or substituted aryl or heteroaryl group, and R5 is H or alkyl, which comprises a) reacting a compound of formula (II) with a chlorinating agent or b1) initially reacting a compound of formula (IV) with a compound of formula (V) and b2) further reacting the compound of formula (II) obtainable thereby, with or without intermediate isolation, with a chlorinating agent, to intermediates used in this process, to the use of these intermediates and to a process for the preparation of these intermediates.
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申请公布号 |
WO9720829(A1) |
申请公布日期 |
1997.06.12 |
申请号 |
WO1996IB01329 |
申请日期 |
1996.12.02 |
申请人 |
NOVARTIS AG;SZCZEPANSKI, HENRY;GOEBEL, THOMAS;HUETER, OTTMAR, FRANZ;O'SULLIVAN, ANTHONY, CORNELIUS;SENN, MARCEL;RAPOLD, THOMAS;MAIENFISCH, PETER;PITTERNA, THOMAS |
发明人 |
SZCZEPANSKI, HENRY;GOEBEL, THOMAS;HUETER, OTTMAR, FRANZ;O'SULLIVAN, ANTHONY, CORNELIUS;SENN, MARCEL;RAPOLD, THOMAS;MAIENFISCH, PETER;PITTERNA, THOMAS |
分类号 |
C07D277/20;C07D;C07D277/32;C07D277/36;C07D417/06;C07D417/12;C07D417/14;(IPC1-7):C07D277/32 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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