3-(4-subst.-piperidinyl-1)-1-(3,4-dichlorophenyl)propyl carbamates and ureas and derivatives as novel neurokinin antagonists

摘要

Compounds of formula I wherein Q1, Q2, Q3, and Q4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists Substance P and NKA, useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.