| 发明名称 |
Activatable fibrinolytic and anti-thrombotic proteins |
| 摘要 |
PCT No. PCT/GB90/01912 Sec. 371 Date Jun. 4, 1992 Sec. 102(e) Date Jun. 4, 1992 PCT Filed Dec. 7, 1990 PCT Pub. No. WO91/09118 PCT Pub. Date Jun. 27, 1991Proteinaceous compounds are activatable by enzymes of the clotting cascade to have fibrinolytic or clot formation inhibition activity. For example, a plasminogen analogue is activatable to plasmin by thrombin or Factor Xa. Fibrinolytic or clot formation inhibition activity is therefore directed to the site of clot formation.
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| 申请公布号 |
US5637492(A) |
申请公布日期 |
1997.06.10 |
| 申请号 |
US19920854603 |
申请日期 |
1992.06.04 |
| 申请人 |
BRITISH BIOTECH PHARMACEUTICALS |
发明人 |
DAWSON, KEITH;EDWARDS, RICHARD M.;FORMAN, JOAN M. |
| 分类号 |
A61K38/46;A61K38/00;A61K38/48;A61K38/55;A61P7/02;C07K7/64;C07K14/00;C07K14/315;C07K14/745;C07K14/81;C07K14/815;C07K19/00;C12N;C12N1/19;C12N1/21;C12N5/10;C12N9/48;C12N9/64;C12N9/68;C12N9/70;C12N9/72;C12N15/09;C12N15/15;C12N15/57;C12N15/62;C12N15/81;C12N15/85;C12P21/02;(IPC1-7):A61K38/43;C12N15/59 |
主分类号 |
A61K38/46 |
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