| 摘要 |
PROBLEM TO BE SOLVED: To express a stereo structure of protein as a whole in an easily understandable manner by a matrix while extracting a partial structure of the protein using the matrix. SOLUTION: In view of hierarchy noted in a stereo structure of protein, a matrix having a hierarchy corresponding thereto is used to express the stereostructure of protein. As regard to a secondary structure packing as illustrated in (a), interaction between individual secondary structures is described at the upper right portion and positional relationship therebetween at the lower left portion as shown by (c) to build a matrix. As regard to a part of the matrix as illustrated in (c), interaction between residual amino groups is represented by a matrix as shown by (d). In the interaction and positional relationship between the secondary structures, the secondary structure is abstracted as vector and the representation thereof is made by an angle therebetween and the minimum of all distances between carbons. To express a main chain structure, two facial angles (ϕ,ψ,ω) and a distance betweenαcarbons are used. Characteristic partial structure is extracted by comparing matrixes between the proteins.
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