发明名称 |
Treatment and control of ocular development |
摘要 |
A composition for the inhibition of the abnormal postnatal axial growth of the eye of a maturing animal which comprises a pharmaceutically effective amount of a muscarinic pharmacological antagonist relatively selective for blocking the cholinergic receptors in cells of the brain, neural tissue and/or neural ganglia but less selective for blocking the cholinergic receptors of the cells of smooth muscles at the front of the eye, said antagonist present in a carrier or diluent suitable for ocular administration. A suitable antagonist is pirenzepine. Other suitable antagonists are telenzepine and o-methoxy-sila-hexocyclium.
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申请公布号 |
US5637604(A) |
申请公布日期 |
1997.06.10 |
申请号 |
US19940268035 |
申请日期 |
1994.06.29 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
LATIES, ALAN M.;STONE, RICHARD A. |
分类号 |
C07D405/06;A61K31/00;A61K31/14;A61K31/16;A61K31/27;A61K31/415;A61K31/4178;A61K31/46;A61K31/495;A61K31/55;A61K31/695;A61K45/00;A61P27/02;A61P27/10;A61P43/00;(IPC1-7):A61K31/42 |
主分类号 |
C07D405/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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