摘要 |
FIELD: organic chemistry, pharmacology. SUBSTANCE: compounds have formula (I) given in specification where each of dotted line independently optional bond; Rsubstituent is atom of hydrogen, atom of halogen, C-alkyl, hydroxy group or C-alkyloxy group; Rsubstituent is atom of hydrogen, C-alkyl or atom of halogen; fragment -B=D is bivalent radical having formula Ror -C(R)=N - (a-1); and substituents -N=C(R)- (a-2) and Rare atom of hydrogen, R-alkyl, ethenyl being substituted by hydroxycarbonyl or by C-alkyloxycarbonyl, C-alkyl is substituted by hydroxycarbonyl or by C-alkyloxycarbonyl, hydroxy-C-alkyl, formyl or hydroxycarbonyl C, Rsubstituent may be phenyl or pyridinyl; substituent L is atom of hydrogen; C-alkyl, substituted C-alkyl, C-alkenyl, C-alkenyl is substituted by aryl; or L substituent is radical with formula -AIk-Y-Het(b-1), -AIk-NH-CO-Het(b-2) or -AIk-Het(b-3). EFFECT: improved quality. |