Process for constructing transgenic animals

摘要

A process for easily constructing transgenic mammals comprising injecting into the amnion fluid of a mammal a composition for gene introduction containing a compound which has affinities for both DNA and the embryo of the mammal or the fetal body surface thereof and a vector for gene introduction. This process enables stage-specific gene introduction at various stages of the development or site-specific gene introduction which cannot be achieved by the conventional techniques.