| 摘要 |
PROBLEM TO BE SOLVED: To obtain an amino acid useful as a raw material for foods, medicines and agrochemicals, etc., by treating an aldehyde cyanohydrin with a bacterium capable of hydrolyzing a cyano group in an aqueous medium in the presence of ammonia or an ammonium salt. SOLUTION: A cyanohydrin of formula I [R<1> is a (substituted) alkyl, phenyl, pyridyl, furyl or thienyl; (n) is an integer of 0-4] (e.g. mandelonitrile) is treated with a bacterium capable of hydrolyzing a cyano group of the cyanohydrin [e.g. Acinetobacter sp. BC9-2 (FERM BP-3317), etc.] or its treated material in an aqueous medium in the presence of ammonia and/or an ammonium salt (e.g. ammonium sulfate, etc.) to efficiently give the objective amino acid (e.g. phenylglycine) of formula II useful as a raw material for foods, medicines and agrochemicals, etc. |
