| 摘要 |
<p>Here we report a study on a reaction sequence on solid phase, suitable for the generation of molecular diversity on small heterocycles of the pyrazole and isoxazole type. For each reaction, suitable conditions on solid phase were worked out and a variety of reactive agents (building blocks) was utilized in an effort to grasp the system's breadth of applicability. The inventive reaction sequence can be applied, for example, to exploit by the combinatorial approaches of the split and mix concept.</p> |
