摘要 |
The use of a compound of general formula (I) or a salt thereof as a medicament is provided, in which n represents an integer from 0 to 4; m represents an integer 0 or 1; each R independently represents a halogen atom or a nitro, cyano, hydroxyl, alkyl, alkenyl, haloalkyl, haloalkenyl, alkoxy, haloalkoxy, haloalkenoxy, amino, alkylamino, dialkylamino, alkoxycarbonyl, carboxyl, alkanoyl, alkylthio, alkylsulphinyl, alkylsulphonyl, carbamoyl, alkylamido, cycloalkyl, aryl or aralkyl group; R<1> and R<2> each independently represent an optionally substituted alkoxy group or together represent a group =O, =S or =N-OR<9>, where R<9> represents a hydrogen atom or an optionally substituted alkyl group; R<3> represents a hydroxyl group, or a group-OL where L is a leaving group, or a group which in vivo is transformed into a group -OL<1> where L<1> is a leaving group; R<6> represents an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl, alkoxy, alkenyloxy, alkynyloxy, cycloalkyloxy, cycloalkenyloxy or aryloxy group; R<7> and R<8> independently represent an optionally substituted alkoxy group or together represent a group =O, =S or =N-OR<9>, where R<9> is as previously defined; wherein R4 and R5 independently represent a halogen atom or an optionally substituted alkyl or alkenyl group, or together with the interjacent carbon atom represent an optionally substituted cycloalkyl or cycloalkenyl group; and A represents a straight or branched chain alkyl or alkenyl group, which may be optionally substituted, preferably with halogen, an acyclic carbon chain of which links the 3 position of the naphthalene ring shown and the moiety -CR<4>R<5>R<6>.
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申请人 |
BRITISH TECHNOLOGY GROUP LIMITED;KHAMBAY, BHUPINDER, PALL, SINGH;SIMMONDS, MONIQUE, SHEELAGH, JACQUARD |
发明人 |
KHAMBAY, BHUPINDER, PALL, SINGH;SIMMONDS, MONIQUE, SHEELAGH, JACQUARD |