发明名称 |
NOVEL NON-PYROGENIC BACTERIAL STRAINS AND USE OF THE SAME |
摘要 |
The present invention provides gram-negative bacterial strains that produce substantially pure non-pyrogenic lipopolysaccharide or lipid A. The present invention also relates to a use of said strains for the preparation of non-pyrogenic DNA and use of the same for introducing endogenous or foreign genes into animal cells or animal tissue. Further, the present invention relates to a use of said strains for the preparation of non-pyrogenic recombinant mammalian, protozoan and viral proteins. Furthermore, the present invention relates to a use of said strains for the preparation of non-pyrogenic bacterial vaccines and vaccine vectors. Yet a further use of the present invention relates to a use of said strains for the preparation of non-pyrogenic bacterial proteins and polysaccharides antigens for use as vaccines.
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申请公布号 |
WO9718837(A1) |
申请公布日期 |
1997.05.29 |
申请号 |
WO1996US19875 |
申请日期 |
1996.11.22 |
申请人 |
UNIVERSITY OF MARYLAND AT BALTIMORE;HONE, DAVID, M.;POWELL, ROBERT, J. |
发明人 |
HONE, DAVID, M.;POWELL, ROBERT, J. |
分类号 |
A61K48/00;A61P31/04;C12N15/74;C12P19/04;(IPC1-7):A61K39/02;C12P21/06;C12P19/00;C12P19/34;C12P1/04;C12N15/00;C12N1/12;C12N1/20;C07H21/02 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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