INTERLEUKIN-5 PRODUCTION INHIBITOR

摘要

Object: to provide an erythromycin derivative having a potent interleukin-5 production inhibitory effect. Constitution: an interleukin-5 production inhibitor containing as the active ingredient an erythromycin derivative, such as 6-O-methylerythromycin A 9-ÄO-(2-chlorophenylmethyl)oximeÜ, 6-O-methylerythromycin A 9-ÄO-(3-methoxy-4-t-butylbenzyl)oximeÜ 11,12-cyclic carbonate or 11-amino-9-N, 11-N-cyclic ethylene-9-deoxo-11-deoxy-6-O-methylerythromycin A 9-benzylamine 11-N, 12-O-cyclic carbamate, or a medicinally acceptable acid-addition salt thereof.