| 发明名称 |
TRICYCLIC BENZAZEPINE ANTAGONISTS OF VASOPRESSIN, METHOD OF SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT |
| 摘要 |
FIELD: organic chemistry. SUBSTANCE: product: tricyclic compounds of the general formula (I)showing antagonistic activity on V- and/or V-receptors and showing antagonistic activity in vivo with respect to vasopressin. Invention relates to method of use of these compounds for diseases control exhibiting excessive renal water absorption and method of synthesis of these compounds. EFFECT: improved method of synthesis, enhanced effectiveness of treatment. |
| 申请公布号 |
RU94027580(A) |
申请公布日期 |
1997.05.27 |
| 申请号 |
RU19940027580 |
申请日期 |
1994.07.28 |
| 申请人 |
AMERIKAN TSIANAMID KOMPANI |
发明人 |
DZHEJ D.OLBRAJT;MEHRVIN F.REJCH;FUK-VAKH SAM;KSJUMEJ DU |
| 分类号 |
A61K31/395;A61K31/435;A61K31/473;A61K31/55;A61K31/551;A61K31/553;A61K31/554;A61P1/16;A61P9/04;A61P11/00;A61P13/02;A61P15/00;A61P25/00;A61P43/00;C07D221/12;C07D221/18;C07D223/18;C07D223/20;C07D223/22;C07D223/28;C07D225/00;C07D225/08;C07D243/18;C07D243/38;C07D245/04;C07D267/16;C07D267/18;C07D267/20;C07D279/30;C07D281/00;C07D281/14;C07D281/16;C07D285/00;C07D285/38;C07D401/12;C07D405/12;C07D407/12;C07D409/12;C07D471/04;C07D487/04;C07D495/04;C07D498/04;C07D513/04 |
主分类号 |
A61K31/395 |
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