发明名称 Novel inhibitors of peptide binding to mhc class ii proteins
摘要 Compounds of formula (I) are inhibitors of peptide binding to major histocompatibility complex type II proteins and may be used in the treatment and prevention of autoimmune diseases including: rheumatoid arthritis, Type I diabetes, multiple sclerosis, lupus erythematosis, Graves disease and pemphigus. The present invention also provides novel compositions, methods of treatment employing compounds of the present invention and methods of manufacture of the compounds of structural formula (I).
申请公布号 AU7475396(A) 申请公布日期 1997.05.22
申请号 AU19960074753 申请日期 1996.10.25
申请人 MERCK & CO., INC. 发明人 ALAN D ADAMS;A. BRIAN JONES
分类号 A61K38/00;C07C237/22;C07D213/82;C07K5/02 主分类号 A61K38/00
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