Aspergillus niger beta-galactosidase gene

摘要

Disclosed are a cloned cDNA and a cloned genomic DNA, both encoding a beta -galactosidase polypeptide from Aspergillus niger. Also disclosed are beta -galactosidase expression vectors, transformed host cells that overexpress recombinant A. niger beta -galactosidase, and A. niger host cell strains with disrupted endogenous beta -galactosidase genes. Also disclosed are transgenic non-human mammals that express A. niger beta -galactosidase.