A process for easily constructing transgenic mammals comprising injecting into the amnion fluid of a mammal a composition for gene introduction containing a compound which has affinities for both DNA and the embryo of the mammal or the fetal body surface thereof and a vector for gene introduction. This process enables stage-specific gene introduction at various stages of the development or site-specific gene introduction which cannot be achieved by the conventional techniques.
申请公布号
WO9717843(A1)
申请公布日期
1997.05.22
申请号
WO1996JP03359
申请日期
1996.11.15
申请人
DNAVEC RESEARCH INC.;MORISHITA, RYUICHI;KANEDA, YASUSHI;OGIWARA, TOSHIO;SAKATA, TSUNEAKI;HASEGAWA, MAMORU