Process for preparing acetoxyazetidinone derivative and intermediates thereof

摘要

An N-Ä2-(1-hydroxyethyl)-3-oxopropylÜamine compound of the formula ÄIIIÜ: wherein Ring B represents a benzene ring which may be substituted; W represents oxygen atom or sulfur atom; Y represents oxygen atom, sulfur atom or N R<0>, R<0> represents hydrogen atom or a substituent; Z represents a substituted methylene group which contains at least one chiral center; R<5> represents an aralkyloxycarbonyl group or an alkoxycarbonyl group; R<6> represents hydrogen atom, an aralkyl group, an acyloxy group, a tri-substituted silyloxy group or an alkoxy group; or both of R<5> and R<6> bond at their termini and combine with the adjacent nitrogen atom to form phthalimido group, and a process thereof are disclosed. Said compound ÄIIIÜ is useful as a starting compound of beta -lactam antibacterial agents.