| 摘要 |
Improved cyclodextrin formulations for the administration of 5 .beta. steroids including .alpha. etiocholanolone, .beta. etiocholonolone, and etiocholandione are provided. Also provided are cyclodextrin formulations including at least one of the 5 .beta. steroids and DHEA. The formulations are suitable for parenteral administration, particularly intravenous administration and are also suitable for treating a condition which responds to treatment with the 5 .beta. steroids alone or together with DHEA, particularly where it is desired to decrease the amount of DHEA administered, including such conditions as obesity, diabetes syndrome, diabetes-associated hypercorticoidism or combinations thereof, anemic disorders including but not limited to aplastic anemia and anemia associated with renal failure or chemotherapy-induced or radiation-induced anemia or neutropenia, and autoimmune or inflammatory disorders such as lupus erythematosus.
|
