| 摘要 |
PCT No. PCT/JP93/00907 Sec. 371 Date Dec. 29, 1994 Sec. 102(e) Date Dec. 29, 1994 PCT Filed Jul. 2, 1993 PCT Pub. No. WO94/01549 PCT Pub. Date Jan. 20, 1994A polyribonucleotide having a thermodynamically stable loop structure and ribozyme activity and a DNA that codes for the polyribonucleotide. The polyribonucleotide has the following structure <IMAGE> Direct administration of the ribozyme polyribonucleotide of the present invention into the body of a patient enables a target polyribonucleotide in the body to be efficiently cleaved, thereby allowing it to be used as an anti-AIDS drug.
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