发明名称 |
DNA fotospaltning ved bruk av texafyriner |
摘要 |
Methods of cleavage of a polymer of deoxyribonucleic acid using photosensitive texaphyrins are disclosed. A preferred method of use is the site-specific cleavage of a polymer of deoxyribonucleic acid and a preferred texaphyrin is a derivatized texaphyrin having binding specificity, in particular, a texaphyrin covalently coupled to a site-directing molecule, preferably an oligonucleotide. |
申请公布号 |
NO971317(A) |
申请公布日期 |
1997.05.16 |
申请号 |
NO19970001317 |
申请日期 |
1997.03.20 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;PHARMACYCLICS INC |
发明人 |
MAGDA, DARREN;SESSLER, JONATHAN L.;IVERSON, BRENT L.;SANSOM, PETRA I.;WRIGHT, MEREDITH;MODY, TARAK D.;HEMMI, GREGORY W. |
分类号 |
C12N15/09;A61K31/70;A61K38/00;A61K38/22;A61K39/395;A61K41/00;A61K47/48;A61K49/00;A61K49/06;A61K49/08;A61K51/04;A61L2/00;B01J31/06;B01J31/16;B01J31/18;C07D487/22;C07H21/00;C07H21/04;C12N15/113;(IPC1-7):C07H21/04;A61K48/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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