QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

摘要

Novel quinoline derivatives and quinazoline derivatives represented by general formula (I) which have an inhibitory effect on the autophosphorylation of growth factor receptors originating in platelets and pharmaceutically acceptable salts thereof; pharmaceutical compositions containing these compounds; and a method for treating diseases relating to the abnormal proliferation of cells such as the proliferation of tumors, wherein R1 and R2 represent each H or C1-4 alkyl, or R1 and R2 together form C1-3 alkylene; X represents O, S or CH2; W represents CH or N; and Q represents substituted aryl or substituted heteroaryl.