| 摘要 |
<p>The invention relates to methods for the regulation in a vertebrate animal or human subject of at least one of lipid and glucose metabolism by the daily administration of growth hormone at a predetermined time of day. More specifically, this invention relates to methods for the improvement of one or more metabolic indices associated with lipid and glucose metabolism disorders, especially those associated with Type II diabetes, also known as non-insulin dependent diabetes mellitus (NIDDM), whereby the improvements persist over an extended period of time after cessation of treatment, wherein the method comprises the daily administration of growth hormone at a predetermined time of day. These indices include body fat stores, hyperlipoproteinemia, hypertriglyceridemia, insulin resistance, hyperinsulinemia, and hyperglycemia.</p> |
