发明名称 |
4-PHENYL-4-OXO-BUTANOIC ACID DERIVATIVES WITH KYNURENINE-3-HYDROXYLASE INHIBITING ACTIVITY |
摘要 |
4-phenyl-4-oxo-butanoic acid derivatives for use in the treatment of the human or animal body by therepy; particularly as kynurenine-3-hydroxylase inhibitors, in the prevention and/or treatment of a neurodegenerative disease wherein the inhibition of such an enyzme is needed. The present invention further comprises a selected class of the above mentioned 4-phenyl-4-oxo-butanoic acid derivatives, their pharmaceutically acceptable salts, a process for their preparation and pharmaceutical compositions containing them.
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申请公布号 |
CA2236450(A1) |
申请公布日期 |
1997.05.15 |
申请号 |
CA19962236450 |
申请日期 |
1996.10.16 |
申请人 |
PHARMACIA & UPJOHN S.P.A. |
发明人 |
SPECIALE, CARMELA;PEVARELLO, PAOLO;VARASI, MARIO;GIORDANI, ANTONIO |
分类号 |
A61K31/16;A61K31/19;A61K31/215;A61K31/275;C07C59/88;C07C59/90;C07C69/738;C07C235/78;C07C255/41;C07C255/57;C07C259/06;C07C323/56;C07C323/62;(IPC1-7):C07C59/88 |
主分类号 |
A61K31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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