发明名称 |
Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic |
摘要 |
A synergistic pharmaceutical combination and composition are disclosed for the treatment of gastritis and peptic ulcer containing a therapeutic amount of a proton pump inhibitor such as e.g., omeprazole or lansoprazole, which increases intragastric pH, and a therapeutic amount of an acid degradable antibacterial compound such as a penicillin or a macrolide. In particular, the combination is directed to the treatment of infections caused by Helicobacter pylori by raising the bioavailability of acid degradable antibacterial compounds.
|
申请公布号 |
US5629305(A) |
申请公布日期 |
1997.05.13 |
申请号 |
US19950441766 |
申请日期 |
1995.05.16 |
申请人 |
ASTRA AKTIEBOLAG |
发明人 |
EEK, ARNE T.;SJOESTRAND, SVEN ERIK |
分类号 |
A61K45/06;A61B17/04;A61B17/06;A61B17/34;A61F2/00;A61K31/00;A61K31/335;A61K31/43;A61K31/44;A61K31/70;A61P1/00;A61P1/04;(IPC1-7):A61K31/43 |
主分类号 |
A61K45/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|