Trifluoromethylpyrroloindolecarboxylic acid ester and process for production thereof

摘要

PCT No. PCT/JP93/01159 Sec. 371 Date Jun. 14, 1995 Sec. 102(e) Date Jun. 14, 1995 PCT Filed Aug. 19, 1993 PCT Pub. No. WO94/04535 PCT Pub. Date Mar. 3, 1994Trifluoromethylpyrroloindolecarboxylic acid ester derivatives, and optical isomers and pharmaceutically acceptable salts thereof are provided which are represented by the general formula (1): <IMAGE> or the general formula (2): <IMAGE> The compounds are antineoplastic agents which are selective to cancer cells, effective also to solid cancer, and less toxic.