Single chain peptide compounds having hemoregulatory activity

摘要

PCT No. PCT/GB93/01172 Sec. 371 Date Nov. 30, 1994 Sec. 102(e) Date Nov. 30, 1994 PCT Filed Jun. 2, 1993 PCT Pub. No. WO93/24524 PCT Pub. Date Dec. 9, 1993There is disclosed single chain peptide compounds, substituted at a C alpha -atom of a non-terminal amino acid by a group-A which is defined in claim 1. The native alpha -side chain of the C alpha atom bonded group to group -A absent. The peptide derivatives according to the invention are useful for inhibiting cell proliferation, especially myelopoietic and bone marrow cells.