Process for disintegrating cell dispersions or cell suspensions by means of ultrasonication for the purpose of isolating cell constituents

摘要

PCT No. PCT/EP93/03406 Sec. 371 Date Aug. 1, 1994 Sec. 102(e) Date Aug. 1, 1994 PCT Filed Dec. 3, 1993 PCT Pub. No. WO94/13783 PCT Pub. Date Jun. 23, 1994A process capable of being continuously carried out, for disintegrating cell material in the form of dispersions or suspensions in water for the purpose of obtaining cell constituent. Selected parameters permit avoidance of use of solid ultrasonication activators and the establishment of a particular geometry form for the acoustic irradiation container. The parameters include sonotrode immersion angle, length of immersion, ratio of extent of immersion of the sonotrode relative to the acoustic irradiation volume and the ratio of extent of immersion to the solid matter content of the medium to be sonicated.