发明名称 |
Computer-controlled bioreactor system for enzymatic synthesis of L-tryptophan |
摘要 |
Disclosed is an automatic computer-controlled bioreactor system for enzymatic synthesis of L-tryptophan which comprises a bioreactor linked to a computer equipped with an on-line indole assay device, in which the computer controls the feeding of indole, pyruvic acid and/or its salt and an ammonium salt into the bioreactor and feedback-controls the reaction in the bioreactor by indole concentration determined by the on-line indole assay device, wherein the feeding of indole and ammonium salt is controlled by a pre-defined profile that agrees with a tryptophanase activity profile and pyruvic acid and/or its salt is added at a predetermined time.
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申请公布号 |
US5629202(A) |
申请公布日期 |
1997.05.13 |
申请号 |
US19950467523 |
申请日期 |
1995.06.06 |
申请人 |
DEVELOPMENT CENTER FOR BIOTECHNOLOGY |
发明人 |
SU, CHEIN-SHYONG;CHAN, ZEN-JEN;HUANG, WUEN-HSIAN;TSAI, HSIN |
分类号 |
C12M1/36;C12P13/22;(IPC1-7):C12M1/36 |
主分类号 |
C12M1/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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