HETEROCYCLYLHYDROXYBENZOYLGUANIDINES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND METHOD OF ITS PREPARING

摘要

FIELD: organic chemistry. SUBSTANCE: product: heterocyclylhydroxybenzoylguanidines of the formula (I)where: R, Rand Het have the indicated values, and their physiologically acceptable salts show antiarrhythmic properties and act as inhibitors of cellular Na/H-antiporter (anticarrier). EFFECT: improved method of synthesis, enhanced effectiveness.