发明名称 |
DETECTION OF HUMAN alpha -THALASSEMIA MUTATIONS AND THEIR USE AS PREDICTORS OF BLOOD-RELATED DISORDERS |
摘要 |
The invention is based on the discovery that adults having a genotype comprising a hemoglobin alpha -gene deletion are significantly more likely to be hypertensive than adults having a normal ( alpha alpha / alpha alpha ) genotype. The invention provides an improved method for determining a human subject's genotype at the alpha -gene loci; a method of screening a human subject for an increased potential of developing hypertension and other blood-related disorders; and provides an apparatus/kit for screening a human subject for a risk of developing hypertension and other blood-related disorders. |
申请公布号 |
WO9716568(A1) |
申请公布日期 |
1997.05.09 |
申请号 |
WO1996US17565 |
申请日期 |
1996.10.30 |
申请人 |
BOWIE, LEMUEL, J. |
发明人 |
BOWIE, LEMUEL, J. |
分类号 |
C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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