摘要 |
<p>Compounds of Formula I are selective autoreceptor agonists useful in treating disease states involving hyperactivity of dopamine systems: <CHEM> in which X is -(CH2)n-; n is 1-3; R1 is hydrogen, alkyl, hydroxyalkyl, cycloalkyl-methyl, bicyclo-alkylmethyl or -(CH2)mYAr; where m is 04, Y is -CH2-, and Ar is phenyl, halophenyl, alkylphenyl, dialkylphenyl or alkoxyphenyl; R2 is hydrogen or alkyl; R3 is hydrogen, halogen, alkyl, alkoxy or hydroxy; or a pharmaceutically acceptable salt thereof.</p> |