发明名称 |
PROTECTION AGAINST LIVER DAMAGE BY HGF |
摘要 |
<p>The present invention provides methods for preventing occurrence or progression of liver damage using hepatocyte growth factor. In the methods, a preventatively effective amount of the hepatocyte growth factor is administered to the patient. The hepatocyte growth factor can be administered, for instance, prior to administering a hepatotoxic therapy to the patient. The hepatocyte growth factor can further be administered with activin or transforming growth factor-beta to prevent liver damage. Compositions comprising hepatocyte growth factor and activin antagonist or transforming growth factor-beta antagonist are also provided by the invention.</p> |
申请公布号 |
EP0661993(B1) |
申请公布日期 |
1997.05.07 |
申请号 |
EP19930922207 |
申请日期 |
1993.09.15 |
申请人 |
GENENTECH, INC. |
发明人 |
ROOS, FILIP;SCHWALL, RALPH |
分类号 |
C12N15/09;A61K38/00;A61K38/18;A61K38/22;A61K39/395;A61P1/16;C07K14/47;C07K14/475;C07K14/495;C07K16/24;C07K19/00;C12N15/12;(IPC1-7):A61K38/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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