Method for producing an optically active diphosphine

摘要

The present invention provides a method for producing novel optically active diphosphine compounds Ä2,2'-bis(di-substituted phosphino)-1,1'-binaphthyl compoundsÜ that have selectivity such as chemo-selectivity or enantio-selectivity and catalytic activity different from those possessed by conventional BINAP compounds. In a method of the present invention for producing an optically active diphosphine compound, i.e. 2,2-bis(di-substituted phosphino)-1,1'-binaphthyl, 2,2'-bis(trifluoromethanesulfonyloxy)-1,1'-binaphthyl is reacted, in the presence of a transition metal-phosphine complex, with a phosphineoxide compound expressed by the following general formula, A2P(O)H wherein A indicates a phenyl group; a mono- to trisubstituted phenyl group, wherein each substituent in the substituted phenyl group is individually selected from halogen atoms, lower alkyl groups, lower alkoxy groups or lower halogenated-alkoxy groups such that one or more of the substituents may be the same or different; a naphthyl group; a lower-alkyl naphthyl group; or a lower-alkoxy naphthyl group.