发明名称 Stable crystalline tetrahydrofolic acid salts
摘要 Crystalline calcium salt of (6R,S)-, (6R)- and (6S)-tetrahydrofolic acid. Also claimed is the magnesium salt. The crystallisation is preferably performed in a polar medium, preferably water or a mixture of water and an organic solvent most preferably acetic acid or a lower alcohol, at pH 7-10 at an elevated temperature and/or from a dilute solution
申请公布号 ZA9609284(B) 申请公布日期 1997.05.07
申请号 ZA19960009284 申请日期 1996.11.05
申请人 EPROVA A.G. 发明人 HANS RUDOLF MUELLER;MARTIN ULMANN;RUDOLF MOSER;THOMAS AMMANN
分类号 A61K31/519;A61K31/522;A61P33/00;A61P35/00;A61P37/00;A61P39/02;C07D239/00;C07D241/00;C07D475/04 主分类号 A61K31/519
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