| 摘要 |
PROBLEM TO BE SOLVED: To obtain a therapeutic and prophylactic agent for atopic dermatitis containing an essence of plant bodies of a labiate catnip. SOLUTION: This therapeutic and prophylactic agent for atopic dermatitis contains pulverized, chopped and dried plant bodies of a labiate catnip, an extract separated from the processed material with a solvent (e.g. water or an alcohol) or a substance removed from the solvent and an essence which is a fractionated substance thereof as an active ingredient. The extraction is performed by adding the solvent in an amount of 1-20 times based on the plant bodies or their processed material thereto, then dipping the plant bodies, etc., therein at ambient temperature for several days or at a temperature near the boiling point of the solvent for several hours and, as necessary, subsequently removing an insoluble substance. The extract is formulated into an oral administration agent, a parenteral injection or a percutaneous administration agent by further suitably blending optional ingredients therewith. The daily dose for an adult is 5-500mg divided into several portions in the case of the oral administration agent and 1-100mg for the parenteral injection. When the resultant formulation is percutaneously administered as a dermal preparation for external use, 0.01-10wt.% is blended in the dosage form and a proper amount thereof is daily applied to a lesion several times. |
