发明名称 Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance
摘要 Compounds of the formula I <IMAGE> (I) in which R signifies a possibly substituted amino group of the general formula -NR1R2, whereby, independently of one another, R1 and R2 each signify hydrogen, lower alkyl, lower alkenyl or lower alkynyl or R represents a saturated, unsaturated or aromatic heterocyclic ring which can possibly be substituted once or twice by lower alkyl or halogen, alk signifies a valency bond, a methylene, a saturated or unsaturated, straight-chained or branched alkylene chain with 2-6 carbon atoms and R3, R4 and R5, in each case independently of one another, signify hydrogen, lower alkyl or benzyl, as well as their pharmacologically acceptable salts and enantiomers, whereby, for the case that R3=R4=R5=CH3 and alk signifies a valency bond, R cannot be the dimethylamino group, processes for their preparation and medicaments which contain these compounds for the treatment of calcium metabolism diseases.
申请公布号 US5627170(A) 申请公布日期 1997.05.06
申请号 US19950465360 申请日期 1995.06.05
申请人 BOEHRINGER MANNHEIM GMBH 发明人 TSAKLAKIDIS, CHRISTOS;BOSIES, ELMAR;ESSWEIN, ANGELIKA;BAUSS, FRIEDER
分类号 A61K31/66;A61K31/662;A61K31/675;A61P3/00;A61P3/14;C07F9/38;C07F9/40;C07F9/553;C07F9/572;C07F9/58;C07F9/6506;C07F9/6509;(IPC1-7):A61K31/40;C07D203/08;C07D205/04;C07D207/06 主分类号 A61K31/66
代理机构 代理人
主权项
地址