发明名称 |
Endotoxin binding and neutralizing protein and uses thereof |
摘要 |
Endotoxin binding/neutralizing proteins capable of binding endotoxin in vivo, thereby neutralizing the toxic effect or bioactivity of endotoxin which are isolated from a horseshoe crab such as Limulus polyphemus, pharmaceutical compositions and pharmaceutical uses of the proteins, a method of purifying the proteins and an assay for endotoxin based on the proteins, are disclosed.
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申请公布号 |
US5627266(A) |
申请公布日期 |
1997.05.06 |
申请号 |
US19950476940 |
申请日期 |
1995.06.07 |
申请人 |
ASSOCIATES OF CAPE COD, INC. |
发明人 |
WAINWRIGHT, NORMAN R.;NOVITSKY, THOMAS J. |
分类号 |
A61K38/00;B01D15/00;C07K14/435;G01N33/543;G01N33/579;(IPC1-7):C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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