发明名称 |
Rotavirus reassortant vaccine |
摘要 |
The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
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申请公布号 |
US5626851(A) |
申请公布日期 |
1997.05.06 |
申请号 |
US19940353547 |
申请日期 |
1994.12.09 |
申请人 |
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY;THE CHILDREN'S HOSPITAL OF PHILADELPHIA |
发明人 |
CLARK, H. FRED;OFFIT, PAUL;PLOTKIN, STANLEY A. |
分类号 |
A61K39/00;A61K39/12;A61K39/15;A61K39/295;C07K14/14;C12N7/00;(IPC1-7):A61K39/12;C12Q1/70 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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