发明名称 |
Selective antagonists for GABArho receptor |
摘要 |
Novel phosphinic and phosphonic acid derivatives of pyridine, pyrrole and azepine with utility as antagonists of the GABArho receptor are disclosed. These compounds have utility as modulators of the excitability of the central nervous system as mediated by their ability to specifically act on closed-channel binding sites of GABArho receptors.
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申请公布号 |
US5627169(A) |
申请公布日期 |
1997.05.06 |
申请号 |
US19940277735 |
申请日期 |
1994.07.20 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MILEDI, RICARDO;OVERMAN, LARRY E.;MURATA, YOSHINORI;WOODWARD, RICHARD M. |
分类号 |
C07F9/553;C07F9/572;C07F9/59;(IPC1-7):C07F9/58;A61K31/675 |
主分类号 |
C07F9/553 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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