| 摘要 |
A process for producing an adduct of a polymer and a target material which process comprises the steps of (a) reacting tresyl chloride with a polymer of formula (II) (C)c POL - Gg wherein POL is a polymer moiety of valency c+g, C is a capping group and c is zero or a positive number and G is a terminal hydroxyl group reactive with the compound of formula (I) and g is a positive number so as to form a sulphonate ester-activated polymer of formula (III) (C)c POL - (tresyl)g wherein C, POL, -AM, c and g are as defined above (b) reacting the activated polymer of formula (III) with the target material and (c) recovering the adduct of the polymer and the target material, in which process: (i) the polymer of formula (II) is dry as determined by benzene distillation, and (ii) the reaction of the tresyl chloride with the polymer of formula (II) is conducted in an organic solvent which is inert to the reagents and to the product of formula (III) and is anhydrous as obtainable using molecular sieves of 0.3nm; (iii) the reaction of the tresyl chloride with the polymer of formula (II) is conducted in a reaction vessel from which water is excluded; (iv) the activated polymer of formula (III) so produced is recovered and either used directly in step (b) or stored, prior to use in step (b), in the presence of a desiccating agent more hygroscopic than the product of formula (III); and v) the reaction of the activated polymer with the target material is conducted in a non-denaturing medium and non-denaturing temperature with respect to the target material. |
