发明名称 |
DIAGNOSIS OF SUSCEPTIBILITY TO CANCER AND TREATMENT THEREOF |
摘要 |
A method for determining the susceptibility of a patient to cancer comprising the steps (i) obtaining a sample containing nucleic acid derived from the patient; and (ii) contacting the said nucleic acid with a nucleic acid capable of selectively hybridising to the region of human chromosome 10 which region is bounded by DNA defined by the markers D10S541 and D10S215. A nucleic acid capable of selectively hybridising to the region of human chromosome 10 which region is bounded by DNA defined by the markers D10S541 and D10S215 provided that the nucleic acid is not any one of certain YACs, BACs, PACs or ESTs defined herein. Preferably the said nucleic acid is a prostate tumour suppressor gene.
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申请公布号 |
CA2232241(A1) |
申请公布日期 |
1997.05.01 |
申请号 |
CA19962232241 |
申请日期 |
1996.10.22 |
申请人 |
IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED;IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED |
发明人 |
GRAY, IAN CHRISTOPHER;SPURR, NIGEL KAY |
分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K48/00;A61P35/00;C07K14/47;C12N5/10;C12Q1/68;(IPC1-7):C12N15/12;C07H21/00;C07K16/32;A61K39/395;A61K47/48;G01N33/574;A61K31/70;C07K14/82 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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