CONJUGATES OF GONADOTROPIN RELEASING HORMONE

摘要

The present invention provides conjugates of GnRH and an immunogenic carrier protein wherein said GnRH is first coupled to a lysine-containing hydrophilic linear oligopeptide scaffold. The conjugates of the invention are capable of eliciting strong immune response against GnRH, and therefore are useful as immunosterilants for animals, or for therapy in animals and human for steroid hormone dependent tumors, and other conditions such as endometriosis and precocious puberty.