发明名称 |
PHARMACEUTICAL COMPOSITIONS CONTAINING PLATELET AGGREGATION INHIBITORS |
摘要 |
The invention is a pharmaceutical composition for intravenous administration to a patient comprising a) a pharmaceutically effective amount of a compound having formula (I), for example 2-S-(n-Butylsulfonylamino)-3-[4-(4-(piperidin-4-yl)butyloxy)phenyl]propionic acid; b) a pharmaceutically acceptable amount of a citrate buffer effective to provide a pH of between about 5 and 7; and c) a pharmaceutically acceptable amount of a tonicity adjusting agent effective to make the formulation substantially isotonic with the osmotic pressure of the biological system of the patient.
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申请公布号 |
WO9715328(A1) |
申请公布日期 |
1997.05.01 |
申请号 |
WO1996US17193 |
申请日期 |
1996.10.23 |
申请人 |
MERCK & CO., INC.;GELOTTE, KARL, M. |
发明人 |
GELOTTE, KARL, M. |
分类号 |
C07D211/22;A61K9/00;A61K31/445;A61K31/4465;A61K33/14;A61K47/02;A61K47/12;A61P7/02;(IPC1-7):A61K47/02 |
主分类号 |
C07D211/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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