发明名称 Piperazine derivatives
摘要 <p>Compounds of formula <CHEM> where A is an alkylene chain of 1 or 2 carbon atoms optionally substituted by one or more lower alkyl groups, R is hydrogen or lower alkyl, R<1> is an aryl or heteroaryl radical, R<2> is a mono- or bicyclic heterocyclic radical, R<3> is hydrogen, lower alkyl or hydroxy and R<4> is a aryl or heteroaryl radical, and their pharmaceutically acceptable acid addition salts are 5-HT1A binding agents which may be used, for example, for the treatment of CNS - disorders such as anxiety.</p>
申请公布号 GR3022257(T3) 申请公布日期 1997.04.30
申请号 GR19970400024T 申请日期 1997.01.09
申请人 JOHN WYETH & BROTHER LIMITED 发明人 WARD, TERENCE JAMES;WARRELLOW, GRAHAM JOHN
分类号 A61K31/415;A61K31/4184;A61K31/4245;A61K31/44;A61K31/495;A61K31/496;A61K31/505;A61P9/12;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/26;A61P43/00;C07D233/54;C07D233/61;C07D235/06;C07D235/08;C07D239/26;C07D271/06;C07D295/084;C07D295/12;C07D295/125;C07D521/00;(IPC1-7):C07D403/06;C07D413/06 主分类号 A61K31/415
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