| 摘要 |
Substituted heteroaromatic compounds, in particular substituted tricyclic fused compounds in which one terminal ring is pyridine or pyrimidine, are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for example in the treatment of psoriasis, fibrosis, atherosclerosis, restenosis, auto-immune disease, allergy, asthma, transplantation rejection, inflammation, thrombosis, nervous system diseases, and cancer. |
