发明名称 |
Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas |
摘要 |
Method using oxygen removal for extending the useful shelf-life of refrigerated red blood cells. A cost-effective, 4 DEG C. storage procedure that preserves red cell quality and prolongs post-transfusion in vivo survival is described. Preservation of adenosine triphosphate levels and reduction in hemolysis and in membrane vesicle production of red blood cells stored at 4 DEG C. for prolonged periods of time is achieved by removing oxygen therefrom at the time of storage; in particular, by flushing with an inert gas. Adenosine triphosphate levels of the stored red blood cells are boosted in some samples by addition of ammonium phosphate.
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申请公布号 |
US5624794(A) |
申请公布日期 |
1997.04.29 |
申请号 |
US19950473675 |
申请日期 |
1995.06.05 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
BITENSKY, MARK W.;YOSHIDA, TATSURO |
分类号 |
A01N1/02;A61K35/18;(IPC1-7):A01N1/02;A61M37/00 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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