发明名称 |
In vivo oligonucleotide generator, and methods of testing the binding affinity of triplex forming oligonucleotides derived therefrom |
摘要 |
The present invention encompasses improved methods and materials for the delivering of antisense, triplex, and/or ribozyme oligonucleotides intracellularly, and RNA polymerase III-based constructs termed "oligonucleotide generators" to accomplish the delivery of oligonucleotides. Also encompassed by the present invention are methods for screening oligonucleotide sequences that are candidates for triplex formation.
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申请公布号 |
US5624803(A) |
申请公布日期 |
1997.04.29 |
申请号 |
US19940324001 |
申请日期 |
1994.10.13 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
NOONBERG, SARAH B.;HUNT, C. ANTHONY |
分类号 |
C12N15/11;C12N15/113;C12N15/85;C12P19/34;C12Q1/68;(IPC1-7):C12Q1/68;C12N15/63 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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