| 发明名称 |
LIPOSOMAL PHOSPHODIESTER, PHOSPHOROTHIOATE, AND p-ETHOXY OLIGONUCLEOTIDES |
| 摘要 |
An improved delivery system for antisense oligonucleotides involves a liposomal composition, comprising a liposome which consists essentially of neutral phospholipids and an antisense oligonucleotide that is entrapped in the liposome and is selected from the group consisting of phosphodiester oligonucleotides, phosphorothioate oligonucleotides, and p-ethoxy oligonucleotides. 00000 |
| 申请公布号 |
WO9707784(A3) |
申请公布日期 |
1997.04.24 |
| 申请号 |
WO1996US14146 |
申请日期 |
1996.08.26 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
LOPEZ-BERESTEIN, GABRIEL;TARI, ANA, MARIA |
| 分类号 |
C12N15/00;A61K9/127;A61K31/00;A61K31/70;A61K31/7088;A61K38/00;A61K48/00;A61P35/00;C07H21/00;C12N15/113 |
主分类号 |
C12N15/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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