PATIENT-SPECIFIC IMMUNOADSORBENTS FOR EXTRACORPORAL APHERESIS AND METHODS FOR THEIR PREPARATION

摘要

The invention relates to the production of multiple-application patientspecific immunoadsorbents which can be used for extracorporal apheresis in patients suffering from disorders caused by dysregulation of the immune system. Conventional methods are used to isolate the immune complexes from the patient's blood and appropriate methods are applied to separate the immune complexes into antigens and antibodies. The antigens and antibodies thus reactivated are coupled individually or as a mixture covalently to suitable carriers which are used as immunoadsorbents for the patient from whom the immune complexes originate. This facilitates production of specific immunoadsorbents even for patients suffering from rare auto-immune diseases.